The year is 2064, and all is not well. A struggling megacorp makes a drastic decision to stave off impending doom. A psychopathic artificial intelligence thought to be dead rises again, attempting to take over the entire Matrix. And behind the scenes, apocalyptic terrorists prepare to strike at key points around the world, completing their first steps towards a vision of Armageddon. Across the globe, shadowrunners find themselves caught up in these events—how will their actions impact the Sixth World? System Failure is set in 2064, and exposes the events that lead to the technology changes that paved the way for Shadowrun, Fourth Edition.